Why I’m Committing To Seed Cobiotics This Year (Review)
Summary: After 60 days of use, these three new supplements from Seed — the DM-02™ Daily Multivitamin, the AM-02™ Daily Energy + Focus, and the PM-02™ Sleep + Restore — have my energy feeling grounded, consistent, and even my sleep has been more restful. I’m noticing my fingernails and hair are growing faster! These are ideal for folks who want more support than a standard multivitamin provides, and for users who want to streamline their supplement game with a single brand that does it all. These aren’t a fit for folks who are already dialed in on other supplement routines, or folks with highly sensitive stomachs (or if you don’t typically take your supplements with food). If you take any prescription meds, definitely talk to your doctor!
What I love:
- After 60 days of use, I’ve noticed more consistent energy and attention thanks to the DM-02™ Daily Multivitamin’s robust nutritional support; in that time I only got sick once during extensive travel and my recovery time was noticeably shorter than it would have been without the supplement.
- While I wasn’t as consistent with the AM-02™ Daily Energy + Focus, it did have a marked impact on my focus levels throughout the day; as someone who takes stimulants for ADHD, I didn’t use this one as frequently.
- The PM-02™ Sleep + Restore was my very favorite! It smoothed my transition to sleeping, and calmed both my mind and body as I prepared for bed. And even with the melatonin, there’s no grogginess in the morning.
- The subscription is handy, and once you purchase your supplements in their glass bottles, the brand sends subsequent deliveries in lightweight foil packets to save on packaging and shipping.
Things to note:
- While I LOVE the sustainability of glass jars with easy refills, I did break one on my many travels. So, either travel with a plastic case or be more careful than I was!
- These pills are big! At least, larger than other supplements I’ve taken in the past. And with the DM-01 and AM-02, there’s a “yeasty” flavor that sensitive folks might not enjoy.
- Speaking of sensitivity, taking DM-01 with food in your system is highly recommended; I had a couple pretty rough mornings before I figured out I needed to take it with food.
- Individually the cost might not be super prohibitive, but the cost for all three would total about $110 for each month.
Optimal healthspan. Increased longevity. Improved energy.
We’re all bombarded by the world of wellness with new ways to track and “hack” our health in order to be our most vibrant selves. To some extent, I welcome this new era of self-focus; I’ve known for a long while that in order to show up as our best selves for the people we care most about, we first must show up for ourselves. The old “put your oxygen mask on before helping others” spiel that frequent air travelers know all too well.
On the flip side, though, all this talk can put an undue amount of pressure on us to be perfect. Like, somehow, if we forgo all the frivolous pleasures of life and dedicate ourselves to clean living 100% of the time, we’ll transcend to some new level of existence and understanding. At least, that’s how I’ve felt about the wellness world as I try to seek the right balance for myself.
“To some extent, I welcome this new era of self-focus…though, all this talk can put an undue amount of pressure on us to be perfect.”
But as I age (I turned 36 years old in 2026, still young but not that young), I’ve noticed certain things slowing down and progress flattening out. I’m at a threshold, and it’s time to start doing even just a little bit more to support my body as she carries me through this mortal plane. So, in addition to lifestyle tweaks — and some overhauls, tbh — I’m adding in supplements to my daily routine to help me get on track and feeling my best.
Meet Seed and the Co‑Biotics line
All of this is why Seed’s newest additions to their supplement lineup caught my attention: DM-02™ for daily support, AM-02™ for focus and energy, and PM-02™ for sleep. As a former supplement mix-and-matcher, it’s a relief to feel like everything gets handled by the same brand.
“As a former supplement mix-and-matcher, it’s a relief to feel like everything gets handled by the same brand.”
Seed is part wellness brand, part biotech company co‑founded by Ara Katz and Raja Dhir around 2015. The brand’s flagship product was DS‑01, a daily synbiotic that combined clinically‑studied probiotic strains with prebiotics and a heavy emphasis on microbiome education. (I’ve also taken this one and am reminded I need a refill!)
The brand’s core proposition is that a healthy gut can change your life — and their team of scientists and doctors have the experience to prove it.
These new supplements, added to the Seed family in 2025, feature the DM-02™ Daily Multivitamin, the AM-02™ Daily Energy + Focus, and the PM-02™ Sleep + Restore. DM‑02 is an advanced multivitamin with a gut‑directed inner capsule; AM‑02 offers caffeine‑free nootropic support for focus; and PM‑02 leans on low‑dose melatonin, ashwagandha, and microbial metabolites for gentler sleep support. Basically, this trio follows up on the foundation that DS-01 laid by offering a more robust AM/PM routine to support even better microbiome health.
My health context and goals
Why am I adding supplements to my routine now? To put it succinctly, I’ve been through a lot, and it’s catching up with me.
For the longer story: In the past few years, I’ve gained over 30 pounds — I’ve had no pregnancies or health conditions that have impacted my weight. While I don’t believe weight is a health indicator, the physical changes I’ve been through have me thinking more deeply about the processes that are influencing this change (aging and hormones are, of course, big ones!).
“Why am I adding supplements to my routine now? To put it succinctly, I’ve been through a lot, and it’s catching up with me.”
Here’s a sampling of what has happened in the past several years: my career has grown, I moved apartments, I got divorced, said goodbye to two dear grandparents and four beloved house rabbits, adopted two cats, and lost and rebuilt community. This past month alone has seen disrupted routines, general fatigue, and rigorous travel.
There’s not just one conclusion here, but if I had to draw one, it’d be that I’m more stressed these days and the cracks in my wellness routine are starting to show — in my life, on my face, and in my emotional wellbeing.
My current health needs are bountiful to say the least; here are the aspects I’m working on that I feel Seed’s co-biotics will be able to help me with:
- Improving my digestion and achieving that elusive gut-brain health optimization as a busy person with an irregular eating schedule (don’t worry, I’m working on that, too!)
- Improve my focus and daytime energy in a sustainable, noticeable way — in addition to the prescription stimulants I take as-needed for ADHD
- Get rest that’s actually restful (I’m a vivid dreamer, and it impacts me significantly physically, mentally, and emotionally)
How I tested these
I’ve been taking these supplements for around 60 days, and I’m including my adherence rate for full transparency below — you’ll see that I haven’t quite gotten to my goal of daily doses, but it’s a big step forward for me all the same. Plus, I think it’s a little more realistic for those of us who are just starting out on a journey like this!
“I’ve been taking these supplements for around 60 days, and I’m including my adherence rate for full transparency.”
I typically take my prescription medicine first thing in the morning on an empty stomach, and circle back to the multivitamin a few hours later. From there, I take the energy and focus supplement about an hour or two after that, and finally the sleep supplement right at bedtime.
The outcomes I’m sharing here are based on how I’ve felt, as well as some insights pulled in from my Oura ring, smart scale, and other wellness wearables.
My review of Seed’s DM‑02™ Daily Multivitamin
Adherence rate: 80%
Over the past 60 days taking this, I have noticed an uptick in my consistent energy levels (and more since I’ve also added the AM-02 supplement). I traveled 16 days out of the 31 days in March and only got sick once with a pretty short recovery time, a victory I also attribute to the supplements. Typically, travel like that would have taken me out of commission a lot sooner. My nails are growing faster than ever, which is also rare for me. I can’t help but tap-tap my fingers on everything these days. 😀💅
This multi, in particular, did come with some additional considerations. I’ve always been a bit extra sensitive to multis that contain zinc and find that some sit better with me than others. I once even had a nighttime multi routine because they’d make me nauseous every time I took it during my waking hours.
But compared to the basic drugstore multis I’ve taken in the past, DM‑02 feels more intentional in its formulation; I love that it loops in more non-traditional multivitamin ingredients like prebiotic and postbiotic compounds, in addition to 100% of the daily value for 20 essential vitamins and minerals. A one-stop shop!
“It loops in more non-traditional multivitamin ingredients like prebiotic and postbiotic compounds, in addition to 100% of the daily value for 20 essential vitamins and minerals. A one-stop shop!”
With the powerful formulation, though, it’s important to note that sensitive tummies will take some time to adjust. Between a large pill size, a taste I can only describe as “yeasty”, and a need to take this with food, makes it particularly challenging for me. About 15 minutes from taking the dose, I usually burp and taste the supplement all over again, which isn’t my favorite.
If you’ve ever had that multivitamin nausea like me, please, please, please take this daily multi with food! If I take it on an empty stomach, I get nauseous about 30 minutes after taking the supplement — admittedly, I’ve even had to get sick in some bushes on my morning walk because of it (so embarrassing). My guess is that it’s the zinc — possibly even the CoQ10 or the probiotic blend — but either way it gets pretty gnarly if I don’t have a bite to eat first. But that problem disappears completely when I take it on a full stomach.
Overall, if you’re looking for a complete vitamin with extra gut support formulations, this is for you! If you’re patching together other vitamins or have stomach sensitivities, it might not be a fit. At $39.99 a month, you’re certainly making more of an investment than store-brand generic multivitamins (but you are getting a higher quality product in my opinion).
My review of Seed’s AM‑02™ Energy + Focus
Adherence rate: 45%
I haven’t been as good at taking this supplement because I prefer to space it out a little further from the morning multivitamin and my other daily meds. Which means, usually, I get swept up in my day and forget to take it! Also, since I already take a stimulant for my ADHD I don’t usually want to add more energy to my day — I would imagine that if I were to hard-knuckle through a month of no ADHD meds and take this instead I might see more noticeable long-term effects ,but I’m not currently at a point in my life where that’s possible.
Seed’s AM-02 does help with steady, sustainable energy without the jitters of caffeine or the anxiety of my stimulant. (No existential dread as a side effect!) Within about an hour, I feel a bit more grounded and focused, making long afternoon meetings a little less taxing on my mind and body.
“Seed’s AM-02 does help with steady, sustainable energy without the jitters of caffeine or the anxiety of my stimulant.”
I don’t get the same digestive upset with this one! Although the taste is still a little “yeasty,” and I do get that singular burp. But overall, this is a lot more gentle on my system.
If you need something fast-acting and highly energizing, this one might not be for you, but I find it’s a good addition to my weekend routine when I don’t quite need the intensity of a stimulant, or if I’ve already taken a stimulant earlier in the day. It’s a little more affordable than the daily multi, clocking in at $34.99 a month, and since I don’t take it every day I find it’s a useful supplement to keep on hand.
My review of Seed’s PM‑02™ Sleep + Restore
Adherence rate: 90%
Of the three of these supplements, this is the one that has had the most immediately noticeable results, and is the one I remember to take most often since it’s right by my bedside. I fall asleep more easily and faster — my Oura ring sleep latency numbers are usually lower on nights I take this supplement.
“Of the three of these supplements, this is the one that has had the most immediately noticeable results.”
As a vivid dreamer, I do notice that this helps me feel a little more rested even after heavy dream nights. I don’t toss and turn as much, and overall I just feel more steady in my sleep cycle. There’s no grogginess the next morning (which hasn’t always been true for me when it comes to melatonin supplements). Plus, I LOVE bringing this with me when I travel! It helps me sleep a little more soundly when I’m in a new environment and out of my usual routine.
The flavor is nonexistent, and there’s no digestive upset with this one. The one drawback here, which is true for all of these supplements, is that it’s a bit larger than supplements I’m used to taking.
If you’re looking for a knockout sleep aid, this one won’t be for you — but it’s certainly for you if you want a smoother off-ramp from your day into your sleep. At $34.99 for a month, this one gets my full seal of approval for balancing quality, effectiveness, without breaking the bank. If I only recommended one of these three, it’d be the PM-02!
Who Seed’s Co-Biotics are for (and not for)
While I have enjoyed the benefits, the biggest drawbacks for me are taste, size, and sensitivity. Seed’s pills are quite large, and the DM-02 and AM-02 have a flavor to them that doesn’t make me excited to take them. And truly, that does make a difference for me when it comes to easily adding them consistently to my routine.
“While I have enjoyed the benefits, the biggest drawbacks for me are taste, size, and sensitivity.”
Outside of that, Seed’s supplements will land best for someone who already cares about gut health and likes the idea of a science‑y, single‑brand routine: one capsule for nutrients, one for focus, one for sleep. If you’re caffeine‑sensitive, prefer steadier energy over big spikes, or have tried basic melatonin and standard multis and wanted something a little more thoughtful, you’ll probably appreciate what Seed is doing here.
They’re not the best fit if your diet and sleep are already highly dialed in and you rarely notice a difference from supplements, if you’re on a tight budget, or if you’re looking for dramatic, overnight changes. And if you take other prescription medications, these are very much in the “talk to your doctor first” category rather than a casual add‑on to your cart.
Final thoughts
Overall, I’m definitely continuing my commitment to the sleep supplement as I’ve noticed the biggest changes there. I’m also going to revamp my breakfast routine to support the daily multivitamin as well!
“I know I can do better about consuming my daily nutrients with a balanced diet, but I’m happy to have this on hand to support any gaps.”
I know I can do better about consuming my daily nutrients with a balanced diet, but I’m happy to have this on hand to support any gaps. I am going to keep the energy and focus supplement on hand as-needed — since it’s the easiest to forget, I don’t want to push myself too hard just yet.
We’re starting where we can!
Emily McGowan is the Editorial Director at The Good Trade. She studied Creative Writing and Business at Indiana University, and has over ten years of experience as a writer and editor in sustainability and lifestyle spaces. Since 2017, she’s been discovering and reviewing the top sustainable home, fashion, beauty, and wellness products so readers can make their most informed decisions. Her editorial work has been recognized by major publications like The New York Times and BBC Worklife. You can usually find her in her colorful Los Angeles apartment journaling, playing with her two cats, or crafting. Say hi on Instagram or follow along with her Substack, Pinky Promise.