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Our editors have researched and taken clean supplements for years. These are our picks for lactoferrin supplements with high-quality, third-party tested ingredients to support iron absorption, gut health, and immunity

Thereโ€™s been a growing conversation around the benefits of lactoferrin, but what exactly is it, and how can it support our health? Scientific literature describes lactoferrin as a โ€œmiracle moleculeโ€ thanks to its antioxidant, antimicrobial, antiviral, and immune-supporting properties, all of which play a role in supporting overall cellular health.

We scoured the internet to find the best lactoferrin supplements that prioritize the ingredients your body actually needs โ€” all made with third-party-tested ingredients and free from unnecessary additives.

What are the benefits of taking lactoferrin?

Naturally found in cowโ€™s milk, colostrum, and even the human body, lactoferrin stands out for its potential to support iron absorption, gut health, and overall immune function. Research suggests it may help the body absorb and regulate iron more efficiently, making it a popular supplement amongst those looking to support healthy iron levels without some of the digestive discomfort commonly associated with traditional iron supplements. Itโ€™s also praised for its antimicrobial and antiviral properties, which may help support the bodyโ€™s natural defences against harmful bacteria and pathogens. Beyond immune support, lactoferrin has become a favorite for intestinal health, with several studies revealing that lactoferrin can prevent and treat gastrointestinal inflammatory diseases in both animals and humans.

There’s also been a resurgence of interest in lactoferrin supplements as some people are exploring its potential benefit when suffering from long COVID or PCOS. Even those who aren’t dealing with these conditions have noted on Reddit the benefits they’ve experienced when taking lactoferrin supplements โ€” notably less inflammation, swelling, and even support in combating visceral fat. Some of the supplements we’ve included on this list may help support your eye and skin health, so it’s no wonder that lactoferrin is considered a “miracle molecule!” Keep in mind that those who have high iron levels should be cautious before taking lactoferrin, and it’s always best to consult your doctor before starting a new supplement.

Why are clean, third-party tested supplements important?

There are tons of lactoferrin supplements on the market today, meaning itโ€™s important to choose one thatโ€™s been independently verified for safety, quality, and ingredient accuracy. Third-party testing helps confirm that the product contains the ingredients and potency listed on the label, while also ensuring itโ€™s free from unwanted contaminants and unnecessary additives. Choosing a third-party-tested lactoferrin supplement can give you greater confidence that youโ€™re investing in a high-quality product that can effectively support your health and wellness goals.

Our criteria:

After researching, corresponding with brands, and combing through customer reviews, our editors have chosen the best clean lactoferrin supplements to support your overall health. We update this list regularly with new, emerging favorites, and all of our picks are evaluated to meet the following criteria

  • SCIENCE-BACKED | Lactoferrin supplements are rising in popularity, and can offer support for iron absorption and have measured effects on gut health as well as immunity. Weโ€™ve ranked brands based on their clinical and scientific backing.
  • THIRD-PARTY TESTED | Each brand uses high-quality ingredients without synthetic fillers, artificial flavors, dyes, parabens, or unnecessary additives. The options on this list offer third-party testing or purity verification so you can feel confident about what youโ€™re taking.

For more about clean, science-backed supplements, weโ€™ve curated guides for the best natural iron supplements, organic probiotics, and immunity supplements.


1. Perelel

American made
Dairy free
Doctor approved
Eco friendly packaging
Natural materials
Recycled materials
Soy free
Subscriptions available
Third party tested
Vegan
Woman owned

Best For | Pregnancy support
Dose | 1 scoop (11g) per day
Prices Starting At | $51 for 25 servings; discounted subscriptions available

Designed with womenโ€™s wellness in mind, the Daily Resilience Complex from Perelel combines 250 mg of clinically studied lactoferrin with 10 g of bioavailable collagen peptides to support whole-body resilience from the inside out. This unflavored, unsweetened daily powder is backed by science and formulated to support immune health, gut health, joint function, connective tissue, and healthy iron utilization โ€” all areas that are especially important during pregnancy, postpartum, and breastfeeding. The lactoferrin in this supplement supports a healthy immune balance, intestinal barrier function, microbiome health, and iron regulation, while the inclusion of collagen peptides provides key structural amino acids that help support joints, connective tissue, and healthy aging. What makes this thoughtfully formulated powder stand out even further is that it’s rooted in science-backed research and is designed specifically to support women through every stage of life โ€” from pregnancy and postpartum recovery to perimenopause and the stages in between.

Our Editor’s Review | “I often feel “icky” in an indefinable way, and the Daily Resilience Complex helped with that problem too. I have to pair it with a healthy diet and plenty of exercise, but I felt like adding this to my life gave me more energy. It’s hard to explain, but this has made me feelโ€ฆstronger, from the inside. It’s subtle, but I feel like my body is handling my various mom-related chores and responsibilities more effectively. I’m moving faster and with more energy, in other words.” – Katherine J Igoe, Contributing Editor [Read our full review.]

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2. Codeage

American made
Eco friendly packaging
Gluten free
Soy free
Third party tested

Best For | Liposomal delivery
Dose | 1 capsule per day
Prices Starting At | $99 for 60 servings

If youโ€™re looking for a more advanced lactoferrin formula, Codeage‘s Liposomal Lactoferrin+ is a great pick. What makes this formula especially unique is the addition of vitamin C and sunflower-derived phospholipids alongside 300mg of bovine lactoferrin, which help support effective delivery and absorption. Vitamin C pairs particularly well with lactoferrin thanks to its role in supporting immune function and iron metabolism, while the phospholipids help protect and transport the active compounds more efficiently throughout the body. These capsules are also non-GMO, soy-free, and gluten-free, and manufactured in the USA in a cGMP-certified facility for quality and purity. Learn more about Codeage’s manufacturing, sourcing, and testing process here.


3. Life Extension

American made
Gluten free
Science backed
Subscriptions available
Third party tested
Vegetarian

Best For | Eye health support
Dose | 1 capsule per day
Prices Starting At | $45 for 60 servings; discounted subscriptions available

Life Extension is an American-owned vitamin and supplement company manufacturing 99% of its supplements right here in the USA. Their gluten-free and non-GMO lactoferrin capsules keep things simple, delivering 300mg lactoferrin derived from bovine whey in a single daily capsule. Beyond promoting a healthy immune system response and the growth of beneficial probiotic bacteria in the gut, emerging research also suggests that lactoferrin may provide benefits for eye health, adding another layer of wellness support to the formula. Life Extension backs its products with more than 40 years of science-driven research and a commitment to product transparency, premium-quality ingredients, and scientifically validated formulations.

Customer Review | “My iron was within the “lab ranges” but was less than optimal. Then I tried for 4 months to raise with iron supplement but barely increased. After stopping all iron supplements, I took this for 3 weeks, stopped for 1 week and retested. It put my iron to optimal levels and still stayed with “lab ranges” – Anonymous (Read all reviews.)


4. Nutricost

American made
Budget friendly
Gluten free
Subscriptions available
Third party tested
Vegetarian

Best For | Affordability
Dose | 1 capsule per day
Prices Starting At | $33 for 60 servings; discounted subscriptions available

If youโ€™re looking for a straightforward, affordable lactoferrin supplement that still checks all the important quality boxes, look to Nutricost‘s Lactoferrin Capsules. Each bottle comes with two months’ worth of lactoferrin in convenient travel-friendly capsules. This formula is vegetarian-friendly, non-GMO, gluten-free, and made in the USA in a GMP-compliant facility using globally sourced ingredients. The brand also prioritizes transparency and safety with independent third-party testing to help verify quality and label accuracy. With plenty of glowing 5-star reviews and a 60-day money-back guarantee, this supplement offers everything (and more) in a lactoferrin formula.

Customer Review | “Nutricost is a solid brand. These lactoferrin pills are easy to swallow and have no discernable taste or odor. A good addition to my supplement routine, I have been taking them daily and have experienced no ill effects.” – Z (Read all reviews.)


5. MyImmunity

American made
Science backed
Third party tested

Best For | Teens; sensitive skin
Dose | 1 capsule per day
Prices Starting At | $60 for 30 servings

MyImmunity Pure Lactoferrin is a great supplement for teens and anyone struggling with breakouts, thanks to its simple, science-backed approach to supporting clearer, healthier skin from the inside out. Each delayed-release capsule contains just one clinically researched ingredient โ€” 300 mg of pure lactoferrin โ€” in a highly bioavailable freeze-dried form designed to preserve its potency and effectiveness. Within the first 1โ€“2 weeks of starting this supplement, you can expect calmer skin, reduced redness, and fewer active breakouts. By around month three, studies suggest you may see significant improvements in acne lesion count, skin tone, and post-breakout redness, while continued use beyond six months can help support long-term skin balance, smoother texture, and fewer hormonal flare-ups. This formula is also 100% drug-free, designated GRAS (Generally Recognized As Safe) by the FDA, and rigorously third-party tested.

Customer Review | “Iโ€™ve tried every topical and diet change out there, but nothing made a lasting difference until this. My breakouts around my chin are almost gone and my skin feels balanced for the first time in years.” – Melissa R. (Read all reviews.)


Featured image is from Perelel


Silsila Bahrami is a Contributing Editor at The Good Trade. She has a BA in Communications and Marketing from York University and has been writing and fact-checking the latest happenings in sustainable fashion, beauty, lifestyle, and home goods since 2023. When not writing or editing, you can find her at the yoga studio, catching the latest flicks, or testing a new matcha recipe. Say hi on Instagram!